Leukemia, like other cancers, results from mutations in the DNA. Certain mutations can trigger leukemia by activating oncogenes or deactivating tumor suppressor genes, and thereby disrupting the regulation of cell death, differentiation or division.
Leukemia symptoms vary, depending on the type of leukemia. Common leukemia signs and symptoms includeIn leukemia, the mutations tell the blood cells to continue growing and dividing. When this happens, blood cell production becomes out of control.
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Leukemia symptoms include: Weakness, tiredness and fatigue. This can be caused by the leukemia itself or by the low levels of hemoglobin seen in many leukemia patients. Fever and frequent infections due to low counts of healthy white blood cells. Excessive sweating or night sweats.
The first signs of leukemia will vary by what kind of leukemia you have. With some forms of leukemia, you might not have any symptoms at first. Signs of leukemia in adults are related to the cancer cells in your blood.
Common signs and symptoms of leukemia include anemia, bruising and bleeding, infections, and fevers. Learn more about these symptoms at MSK today.
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